What is the primary objective of using Adeno-Associated Virus (AAV) to engineer cancer cells?

The primary goal is to utilize AAV vectors to deliver therapeutic genes directly into cancer cells, transforming them into "factories" that express immunostimulatory molecules or pro-apoptotic factors. This approach aims to bypass the systemic toxicity often associated with traditional therapies by localizing the treatment within the tumor microenvironment.

For more: Engineering Cancer Cells by Adeno-associated Virus