Discussions
What types of in vitro BBB models does Creative Biolabs utilize?
2 hours ago by sg
Blood-Brain Barrier (BBB) Study
The platform relies on advanced models to simulate human physiology:
Co-culture Systems: Utilizing primary or immortalized brain endothelial cells, astrocytes, and pericytes to mimic the neurovascular unit (NVU).
Dynamic Flow Systems: Simulating hemodynamics and shear stress to improve the model's physiological relevance.
Standard Assays: Including PAMPA (Parallel Artificial Membrane Permeability Assay) for high-throughput screening of passive diffusion.
